Andes was a founding member of Spirit and played bass on their first four albums. Mark Andes co-founded the band Jo Jo Gunne and the band had a Top 40 hit with the single “Run, Run, Run”. He joined the band Firefall in 1975 and they had a Top 10 hit with the single “You Are the Woman”. Andes joined the band Heart and appeared on their albums including Passionworks in 1983 and Heart in 1985.